The mouth has a natural ability to protect against oral infections and disease. This is mostly due to the remarkable properties of saliva and its protective enzymes and proteins, which help to maintain a balanced oral microbiome and healthy mouth.1,2
For the first time, a toothpaste containing natural enzymes and proteins has been shown to significantly shift the oral microbiome at species level. Brushing with Zendium resulted in a microbial community with a stronger association with health.3*
Real data visualisation of bacterial species whose relative abundance changed significantly over 14 weeks of brushing with Zendium.
In the 14-week study, brushing with Zendium significantly increased health-associated bacteria and decreased disease-associated bacteria, resulting in a microbial community with a stronger association with health.3* No such change was seen with standard fluoride toothpaste in this study.
Zendium’s formulation contains natural enzymes and proteins reflecting some of those found in saliva where they are known to contribute to a balanced microbiome.1
*Colostrum is the source of IgG
Zendium’s triple enzyme system of amyloglucosidase, glucose oxidase and lactoperoxidase drives the production of natural salivary antimicrobial components.4,5 Zendium also contains three other ingredients: lysozyme, lactoferrin and colostrum as a source of IgG; that can be found naturally in saliva and work in harmony with enzymes to protect the mouth naturally.1,4,6,7
Zendium has a specially designed formulation without sodium lauryl sulphate (SLS). Instead, the foaming agent is stearylethoxylate, which respects the delicate soft tissues of the mouth, helping to protect epithelial integrity.8,9 This makes Zendium suitable for patients with a sensitive oral mucosa, including those with aphthous ulcers.
*Refers to the oral plaque microbiome and the relative abundance of bacterial species with a known association with gum health or disease after 14 weeks of brushing twice a day with Zendium when compared to baseline.