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ZENDIUM
BIOSCIENCE

BIOSCIENCE ZENDIUM

ZENDIUM – A FIRST IN ORAL CARE

For the first time, a toothpaste containing natural enzymes and proteins has been shown to significantly shift the oral microbiome at species level. Brushing with Zendium resulted in a microbial community with a stronger association with health.3*

Microscope slide
BASELINE and 14 WEEKS
BASELINE
14 WEEKS

TYPES OF BACTERIA*


Health-associated
Disease-associated
No known association

*Refers to the oral plaque microbiome and the relative abundance of bacterial species with a known association with gum health or disease after 14 weeks of brushing twice a day with Zendium when compared to baseline.

1. Adams SE, et al. Sci Rep 2017; 7:43344

ZENDIUM INCREASES HEALTH-ASSOCIATED BACTERIA*

In the 14-week study, brushing with Zendium significantly increased health-associated bacteria and decreased disease-associated bacteria, resulting in a microbial community with a stronger association with health.3*  No such change was seen with standard fluoride toothpaste in this study.

Microbial community

ZENDIUM HAS A FORMULATION INSPIRED BY SALIVA

Zendium’s formulation contains natural enzymes and proteins reflecting some of those found in saliva where they are known to contribute to a balanced microbiome.1

*Colostrum is the source of IgG

Zendium ingredients

ZENDIUM IS KIND TO MOUTHS

Zendium has a specially designed formulation without sodium lauryl sulphate (SLS). Instead, the foaming agent is stearylethoxylate, which respects the delicate soft tissues of the mouth, helping to protect epithelial integrity.8,9 This makes Zendium suitable for patients with a sensitive oral mucosa, including those with aphthous ulcers.

free from harsh chemicals

*Refers to the oral plaque microbiome and the relative abundance of bacterial species with a known association with gum health or disease after 14 weeks of brushing twice a day with Zendium when compared to baseline.

 

REFERENCES

  1. Van ‘t Hof W, et al. Monogr Oral Sci 2014; 24:40–51;
  2. Amerongen AV & Veerman EC. Oral Dis 2002; 8:12-22;
  3. Adams SE, et al. Sci Rep 2017; 7:43344
  4. Lenander-Lumikari M, et al. J Dent Res 1992; 71:484-490;
  5. Unilever données internes.
  6. Berlutti F, et al. BioMetals 2004; 17:271-278;
  7. Lenander-Lumikari M & Loimaranta V. Adv Dent Res 2000; 14:40-47;
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