Oral bacteria
défenses naturelles

THE ORAL
MICROBIOME

THE ORAL MICROBIOME

WE ARE HOME TO A VAST COMMUNITY OF MICROBES

Our body is colonised by millions of bacteria,3 collectively
known as the microbiome.4 Throughout human evolution,
humans and bacteria have co-evolved to exist in a
mutually beneficial, symbiotic partnership that is essential
for human health.1,5,6

Human holobiont

MODERN LIFE CAN DISRUPT THE NATURAL BALANCE OF THE MOUTH

The composition of the oral microbiome is remarkably stable. However, several factors can lead to a predominance of disease-associated bacteria in the mouth: a state of dysbiosis.1

Factors causing dysbiosis

AN IMBALANCED MICROBIOME RISKS DISEASE

If symbiosis is not restored, dysbiosis can increase the risk of oral problems, including caries, periodontal disease and halitosis.1,2

Oral Problems

A NEW GOAL – RESTORE THE ORAL MICROBIOME BALANCE

An expert consensus paper incorporates the latest evidence on the oral microbiome to make new recommendations for clinical care:1

"It is pivotal that both patients and healthcare professionals embrace the concept of a balanced oral microbiome and its importance in oral and systemic health."1

A new landmark study now shows that Zenidum is clinically proven to promote a balanced oral microbiome.*8

Dental check

*Refers to the oral plaque microbiome and the relative abundance of bacterial species with a known association with gum health or disease after 14 weeks of brushing twice a day with Zendium when compared to baseline.

 

REFERENCES

1. Kilian M, et al. Br Dent J 2016; 221:657–666;

2. Marsh PD. Br Dent J 2012; 212:601–606;

3. Sender R, et al. Cell 2016; 164:337–340;

4. Dewhirst FE, et al. J Bacteriol 2010; 192:5002–5017;

5. Gibert A & Hazard L. J Ecology 2013; 101:743–752;

6. Human Microbiome Project Consortium. Nature 2012; 486:207–214;

7. van ‘t Hof W, et al. Monogr Oral Sci 2014; 24:40–51;

8. Adams SE, et al. Sci Rep 2017; 7:43344

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